What happens if I overdose Cozaar? Seek emergency medical attention or call the Poison Help line at What losartan I avoid while taking losartan Cozaar? Drinking alcohol can further lower your blood pressure and may increase certain mgm effects of losartan, losartan 50 mgm.
Do not use potassium supplements or salt substitutes while you are taking losartan, unless your doctor has told you to.
In patients losartan heart failure, losartan 50 mgm, with or without renal impairment, there is - as with other drugs acting on the renin-angiotensin system - a risk of severe arterial hypotension, and often acute renal impairment. Aortic and mitral valve stenosis, obstructive hypertrophic mgm As with other vasodilators, special caution is indicated in patients suffering from aortic or mitral stenosis, or obstructive hypertrophic cardiomyopathy, losartan 50 mgm.
Ethnic differences As observed for angiotensin converting enzyme inhibitors, losartan and the other angiotensin antagonists are apparently less effective in lowering blood pressure in black people than in non-blacks, possibly because of higher prevalence of low-renin states cialis cura la prostata the black hypertensive population.
Dual blockade of the renin-angiotensin-aldosterone system RAAS There is evidence that the concomitant use of ACE-inhibitors, angiotensin II receptor blockers or aliskiren increases the risk of hypotension, hyperkalaemia and decreased renal function including acute renal failure.
If dual blockade therapy is considered absolutely necessary, losartan 50 mgm, losartan should only occur under specialist supervision and subject to frequent close monitoring of renal function, electrolytes and blood mgm. Patients should be observed for clinical signs of fluid or electrolyte imbalance, e.
Periodic determination of serum electrolytes should be performed at appropriate intervals in such patients. Dilutional hyponatraemia may occur in oedematous patients in hot weather.
Metabolic and endocrine effects Thiazide therapy may impair glucose tolerance. Dosage adjustment of antidiabetic agents, including insulin, may be required see section 4, losartan 50 mgm.
Latent diabetes mellitus may become manifest during thiazide therapy. Thiazides may decrease urinary calcium excretion and may cause mgm and slight elevation of serum calcium.
Marked hypercalcemia may be losartan of hidden hyperparathyroidism. Thiazides should be discontinued before carrying out tests for parathyroid function. Increases in cholesterol and triglyceride levels may be associated with thiazide diuretic therapy. Because losartan decreases uric acid, losartan in combination with hydrochlorothiazide attenuates the diuretic induced hyperuricemia.
Hepatic impairment Thiazides should be used with caution in patients with panadol antigripal generico hepatic function or progressive liver disease, as it mgm cause intrahepatic cholestasis, losartan 50 mgm, and since minor alterations of fluid and electrolyte balance may precipitate hepatic losartan.
Other In patients receiving thiazides, hypersensitivity reactions may occur with or without a history of allergy or bronchial asthma.
Exacerbation or activation of systemic lupus losartan has been mgm with the use of thiazides. Your doctor may need to adjust your diabetes medication, exercise programor diet.
This medication may make you more sensitive to the sun, losartan 50 mgm. Limit your time in the sun. Avoid tanning booths and sunlamps.
Use sunscreen and wear protective clothing when outdoors.
Ketoconazole did not affect the conversion of Losartan to the active metabolite mgm intravenous administration of Losartan, and erythromycin had no clinically significant effect after oral administration. Fluconazole, an losartan of P 2C9, losartan 50 mgm, decreased active metabolite concentration and increased Losartan concentration. The pharmacodynamic consequences of concomitant use of Losartan and inhibitors of P 2C9 have not been examined.
Subjects who do not metabolize Losartan to active metabolite have been shown to have a specific, rare defect in cytochrome P 2C9.
These data suggest that the conversion of Losartan to its active metabolite is mediated primarily by P 2C9 mgm not P 3A4. As with other drugs that block angiotensin II or its effects, concomitant use of potassium-sparing diuretics e.
Increases in serum lithium concentrations and lithium toxicity have been reported during concomitant administration of lithium with angiotensin Losartan receptor antagonists. Monitor serum lithium levels during concomitant use. In patients who are elderly, losartan 50 mgm, volume-depleted including those on diuretic therapyor with compromised renal function, co-administration of NSAIDs, including selective COX-2 inhibitors, with angiotensin II receptor antagonists including Losartan may result in deterioration mgm renal function, including possible acute renal failure.
These effects are usually reversible. Dual blockade of the RAS with angiotensin receptor blockers, ACE inhibitors, or aliskiren is associated with increased risks of hypotension, syncope, hyperkalemia, and changes in renal function including acute renal failure compared to monotherapy.
Patients receiving the combination of Losartan and lisinopril did not obtain any additional benefit compared to monotherapy for the combined endpoint of decline in GFR, end stage renal disease, or death, but experienced an increased incidence of hyperkalemia and acute kidney injury compared with the monotherapy group. Closely monitor blood pressure, renal function, and electrolytes in patients on Losartan potassium tablets and other agents that affect the RAS. Do not co-administer aliskiren with Losartan potassium tablets in patients with diabetes.
Losartan Increasing Serum Potassium Coadministration of Losartan with other drugs that raise serum potassium levels may result in hyperkalemia.
Monitor serum potassium in such patients. Lithium Increases in serum lithium concentrations and lithium toxicity have been reported during concomitant administration of lithium with angiotensin II receptor antagonists. Dual Blockade of the Renin-Angiotensin System RAS Dual blockade of the RAS with angiotensin receptor blockers, ACE inhibitors, or aliskiren mgm associated with increased risks of hypotension, syncope, hyperkalemia, and changes in renal function including acute renal failure compared to monotherapy.
Losartan most patients no benefit has been associated with using two RAS inhibitors concomitantly. In general, losartan 50 mgm, avoid combined use of RAS inhibitors.
Closely monitor blood pressure, renal mgm, and electrolytes in patients on Losartan potassium and other agents that affect the RAS. If it does, it losartan cause side effects in a child who is breastfed.
Talk to your doctor if you breastfeed your child. You may need to decide whether to stop breastfeeding or stop taking this medication, losartan 50 mgm. Older adults may process drugs more slowly. A typical adult mgm may cause levels of this drug to be higher than normal. This medication losartan not be used in children younger than 6 years.
All possible dosages and forms may not be included here. Your doctor will tell you what dosage is right for you. Your dose, losartan 50 mgm, form, and how often you take it will depend on: The dosage information below is for the conditions that losartan is most often prescribed to treat.
This list may not contain mgm conditions that your doctor can prescribe this drug for. If you losartan questions about your prescription, talk with your doctor.
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