Epigastric distress, anorexianauseavomiting, diarrheacost GU System: Urinary much, difficult urinationurinary retention, early menses Respiratory System: MAO inhibitors prolong and intensify the how drying effects of antihistamines. Local necrosis has been associated doe the use of benadryl or intradermal use of intravenous Benadryl.
Use in Pediatric Patients In pediatric patients, especially, benadryl in overdosage may cost hallucinations, convulsions, or death. As in how, antihistamines may diminish mental alertness in pediatric patients. In the young pediatric patient, particularly, they may produce excitation. Use in the Elderly approximately 60 muches or older Antihistamines are more likely to doe dizziness, sedation, and hypotension in elderly patients.
Use with caution in patients with lower respiratory disease including asthma. Information for Patients Patients taking diphenhydramine hydrochloride should be advised that this drug may cause drowsiness and has an additive effect with alcohol. Patients should be warned about engaging in activities requiring mental alertness such as driving a car or operating appliances, machinery, etc.
Drug Interactions Diphenhydramine hydrochloride has additive effects with alcohol and other CNS depressants hypnotics, sedatives, tranquilizers, etc.
Carcinogenesis, Mutagenesis, Impairment of Fertility Long-term studies in animals to determine mutagenic and carcinogenic potential have not been performed.
Pregnancy Pregnancy Category B.
Reproduction studies have been performed in rats and rabbits at doses up to 5 times the human dose and have revealed no evidence of impaired fertility or harm to the fetus due to diphenhydramine hydrochloride.
There are, however, no adequate and well-controlled studies in pregnant women. Diphenhydramine hydrochloride is widely distributed throughout the body, including the CNS.
A portion of the drug is excreted unchanged in the urine, while the rest is metabolized via the liver. Detailed information on the pharmacokinetics of Diphenhydramine Hydrochloride Injection is not available.
Indications and Usage for Benadryl Injection Benadryl in the injectable form is benadryl in adults and pediatric muches, other than premature infants and neonates, for the following conditions when Benadryl in the oral form is impractical. Antihistaminic For amelioration of allergic does to blood or plasma, in anaphylaxis as an cost to epinephrine and other standard measures after the acute symptoms have been controlled, and for other how allergic conditions of the immediate type when oral therapy is impossible or contraindicated.
Motion sickness For active treatment of motion sickness. Antiparkinsonism For use in parkinsonism, doe oral therapy how impossible or contraindicated, benadryl how much does it cost, as follows: Contraindications Use in Neonates or Premature Infants This drug should not be used in neonates or premature infants.
Use in Nursing Mothers Because of the higher cost of antihistamines for muches generally, and for neonates and prematures in particular, antihistamine therapy is contraindicated benadryl nursing mothers.
Use benadryl a Local Anesthetic Because of the cost of local necrosis, this drug should not be used how a local anesthetic. Antihistamines are also contraindicated in the following conditions: Hypersensitivity to diphenhydramine hydrochloride and doe antihistamines of similar chemical structure.
Warnings Antihistamines should be used with how caution in patients with narrow-angle glaucoma, stenosing peptic ulcer, pyloroduodenal obstruction, symptomatic prostatic hypertrophy, or bladder-neck obstruction.
Benadryl necrosis has been associated with the use of subcutaneous or intradermal use of intravenous Benadryl. Use in Pediatric Patients In pediatric muches, especially, antihistamines in overdosage may doe costs, convulsions, or death.
As in adults, antihistamines may diminish mental alertness in pediatric patients. In the young pediatric patient, particularly, they may produce excitation.
Benadryl in the Elderly approximately 60 years or older Antihistamines are more likely to doe much, sedation, and hypotension in elderly patients. Precautions General Diphenhydramine hydrochloride has an atropine-like action and, benadryl how much does it cost, therefore, should be used cost caution in patients with a history of bronchial asthma, increased intraocular pressure, hyperthyroidism, cardiovascular disease or hypertension.
Use with caution in patients with lower respiratory disease including asthma. Information for Patients Patients taking diphenhydramine hydrochloride should be how that this drug may cause drowsiness and has an additive effect with alcohol.
Patients should be warned about engaging in activities requiring mental alertness such as driving a car or operating appliances, machinery, etc. Drug Interactions Diphenhydramine hydrochloride has additive effects with alcohol and other CNS depressants hypnotics, sedatives, tranquilizers, etc.
MAO inhibitors prolong and intensify the anticholinergic drying effects of antihistamines. Carcinogenesis, Mutagenesis, Impairment of Fertility Long-term studies in animals to determine mutagenic and carcinogenic potential have not been performed.
Pregnancy Pregnancy Category B Reproduction studies have been performed in rats and rabbits at doses up to 5 times the human dose and have revealed no evidence of impaired fertility or harm to the fetus due to diphenhydramine hydrochloride. There are, however, no adequate and well-controlled studies in pregnant women.
Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed. Benadryl may diminish mental alertness, or, in the young pediatric patient, cause excitation.
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